Hans Hoheisen Wildlife Research Stationhttp://hdl.handle.net/2263/176542024-03-29T07:59:19Z2024-03-29T07:59:19ZThe bacterial microbiome of Rhipicephalus sanguineus ticks in the Mnisi community, South AfricaAckermann, RebeccaGall, Cory A.Brayton, Kelly A.Collins, Nicola E.Van Wyk, IlanaWentzel, Jeanette MariaKolo, Agatha OnyemowoOosthuizen, Marinda C.http://hdl.handle.net/2263/798562022-04-08T22:49:21Z2021-01-01T00:00:00ZThe bacterial microbiome of Rhipicephalus sanguineus ticks in the Mnisi community, South Africa
Ackermann, Rebecca; Gall, Cory A.; Brayton, Kelly A.; Collins, Nicola E.; Van Wyk, Ilana; Wentzel, Jeanette Maria; Kolo, Agatha Onyemowo; Oosthuizen, Marinda C.
Rhipicephalus sanguineus, the brown dog tick, is almost exclusively a parasite of domestic dogs and is well adapted to living with its canine host in kennels or human dwellings , where it may also bite people in the safety of their own homes. It is known to transmit various tick-borne diseases. In the Mnisi community, an
area of high rural poverty in Bushbuckridge, Mpumalanga, South Africa, R. sanguineus is one of the most prevalent ticks found on dogs. The community lies at the human/livestock/wildlife interface where humans are at risk of infection with various tick-borne zoonotic diseases.
Includes bibliographical references; Poster presented at the 27th Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP2019)
2021-01-01T00:00:00ZDetection of zoonotic bacterial pathogens in various hosts in the Mnisi community, Mpumalanga, South Africa using a microbiome sequencing approachKolo, Agatha OnyemowoCollins, Nicola E.Brayton, Kelly A.Blumberg, Lucille HellenFrean, John A.Wentzel, Jeanette MariaGall, Cory A.Oosthuizen, Marinda C.http://hdl.handle.net/2263/798262022-04-08T22:49:47Z2021-01-01T00:00:00ZDetection of zoonotic bacterial pathogens in various hosts in the Mnisi community, Mpumalanga, South Africa using a microbiome sequencing approach
Kolo, Agatha Onyemowo; Collins, Nicola E.; Brayton, Kelly A.; Blumberg, Lucille Hellen; Frean, John A.; Wentzel, Jeanette Maria; Gall, Cory A.; Oosthuizen, Marinda C.
The Mnisi community, an agro pastoral area adjacent to the Kruger National Park, Mpumalanga Province, South Africa, is classified as one of South Africa's 14 rural poverty nodes. It is nestled at the cusp of a human-livestock-wildlife interface. In this area, undifferentiated non-malarial acute febrile illness (AFI) is among the most common presenting sign in patients seeking healthcare at the community clinics. Recent research suggested that zoonotic pathogens either
rodent-borne or tick-borne may be common aetiologies of febrile illness in the community. The study had shown that patients presenting with non-malarial AFI had prior exposure to Bartonella spp., spotted fever group Rickettsia, Coxiella burnetti and Leptospira spp. Low levels of West Nile and Sindbis, but no Rift Valley fever virus exposure were found. In a separate study, partial 16S rRNA gene sequences closely related to the zoonotic tick-borne rickettsial pathogen Anaplasma phagocytophilum have been detected in domestic dogs in the area and R. africae was found in ticks collected from dogs. Research in the area has also found rodents to be common and abundant with 76% of households reporting that they have seen rodents around their homes; of which 62%
saw them on a daily basis. The active surveillance for potential pathogens in febrile patients, wild rodents, domestic dogs and cattle is thus of utmost importance in order to identify emerging zoonotic pathogens which could impact human health and livestock production in the Mnisi area and beyond.
Includes bibliographical references; Poster presented at the 30th Meeting of the American Society for Rickettsiology (ASR), 2019
2021-01-01T00:00:00ZBacterial blood microbiome of rodents captured from a human/livestock/wildlife interface in Bushbuckridge, South AfricaKolo, Agatha OnyemowoGall, Cory A.Wentzel, Jeanette MariaKolo, Francis BabamanVan Heerden, HenrietteCollins, Nicola E.Brayton, Kelly A.Oosthuizen, Marinda C.http://hdl.handle.net/2263/798252022-04-08T22:49:42Z2021-01-01T00:00:00ZBacterial blood microbiome of rodents captured from a human/livestock/wildlife interface in Bushbuckridge, South Africa
Kolo, Agatha Onyemowo; Gall, Cory A.; Wentzel, Jeanette Maria; Kolo, Francis Babaman; Van Heerden, Henriette; Collins, Nicola E.; Brayton, Kelly A.; Oosthuizen, Marinda C.
Zoonotic pathogens make up an important and increasing number of emerging and reemerging infectious diseases of humans worldwide. It has been documented that rodents serve as hosts and reservoirs of over 60 zoonotic pathogens that pose significant challenges to human health. The Mnisi community area in Bushbuckridge Municipality, Mpumalanga Province, South Africa is cradled in the heart of a human/livestock/wildlife interface. In this community humans, domestic animals and wildlife have perennial direct and indirect contact. Research in the area has found rodents to be common and abundant with 76% of households reported seeing rodents around their homes. Of that number 62% of the respondents saw them daily. A recent study in the area suggests that rodent-borne zoonoses may be implicated as causes of non-malarial acute febrile illness. In this study, 6.5% of acute febrile illness patients tested positive for the rodent-borne zoonotic pathogen Bartonella spp. on PCR, while 6.8% of patients showed prior exposure to Coxiella burnetti, the cause of Q fever and 2.3% to Leptospira spp. The surveillance of zoonotic pathogens in rodents in this community is thus of utmost importance as the role they play in the transmission of zoonotic pathogens to humans is unknown.
Includes bibliographical references
2021-01-01T00:00:00ZA survey of risk factors with regard to bovine tuberculosis and brucellosis in Mnisi, Mpumalanga Province, South AfricaMolefe, Cisky KgabisaPietersen, MMichel, Anita Luisehttp://hdl.handle.net/2263/798102022-04-08T22:49:41Z2021-01-01T00:00:00ZA survey of risk factors with regard to bovine tuberculosis and brucellosis in Mnisi, Mpumalanga Province, South Africa
Molefe, Cisky Kgabisa; Pietersen, M; Michel, Anita Luise
Cow’s milk forms an essential component of household diets and is an important source of animal protein to poor communities (especially for the young and old). Milk is largely consumed unpasteurised and poses a threat to human health from zoonotic diseases such as bovine tuberculosis (BTB) and brucellosis (Bryan
1983). The recent detection of both infections in the cattle population in the Mnisi area (Matekwe 2012, Musoke unpublished information) prompted an investigation of the risk factors associated with the zoonotic transmission of the causative agents, Mycobacterium bovis and Brucella abortus.
Includes bibliographical references
2021-01-01T00:00:00Z