Browsing by Subject "G protein-coupled receptors (GPCRs)"

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The Brugia malayi neuropeptide receptor-4 is activated by FMRFamide-like peptides and signals via Gα

Anderson, Ross Calley; Newton, Claire L.; Millar, Robert P.; Katz, Arieh A. (Elsevier, 2014-06)

Genetic studies undertaken in the model organism Caenorhabditis elegans have demonstrated the importance of neuropeptidergic signalling in nematode physiology. Disruption of this signalling may have deleterious phenotypic ...
Functional rescue of inactivating mutations of the human neurokinin 3 receptor using pharmacological chaperones

Anderson, Ross Calley; Hanyroup, Sharika; Song, Yong Bhum; Mohamed-Moosa, Zulfiah; Van den Bout, Iman; Schwulst, Alexis C.; Kaiser, Ursula B.; Millar, Robert P.; Newton, Claire L. (MDPI, 2022-04-21)

G protein-coupled receptors (GPCRs) facilitate the majority of signal transductions across cell membranes in humans, with numerous diseases attributed to inactivating GPCR mutations. Many of these mutations result in ...

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